When I develop custom templates for my sites or for customers I usually prefer to stay with the fixed width within 1000px.
First of all you have better control how how layout will be displayed with the fixed width, while fluid layout can move some elements out of intended place.
The 1000px number is based on popular screen size 1280x1024 but you have to keep in mind that many people are using sidebars for bookmarks and other stuff so they loose 250-300 px...
Even if someone has wide screen of 1600px or more - it's almost impossible to concentrate on whole page and some of the content will be left unnoticed.
So this is my general recommendation: fixed width up to 980px...



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